Stability of biochemical reaction networks with general kinetics and distributed time delays
Molnár, Gyula and Vághy, Mihály András and Szederkényi, Gábor (2025) Stability of biochemical reaction networks with general kinetics and distributed time delays. JOURNAL OF MATHEMATICAL CHEMISTRY, 63. ISSN 0259-9791 10.1007/s10910-025-01756-3
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Abstract
Distributed delays play an important role in biological modeling, and are often inevitable to obtain a sufficiently precise quantitative description of certain important processes. It is known from previous studies that mass-action type complex balanced chemical reaction networks (CRNs) containing distributed delays are stable. In this paper, we consider complex balanced biochemical reaction networks with distributed delays, containing a general class of reaction rates including Michaelis–Menten and Hill-type kinetics. We show that for integrable delay distributions defined on a finite time interval, there exists precisely one equilibrium in each stoichiometric compatibility class. The local stability of the equilibria is shown using a logarithmic Lyapunov–Krasovski functional. The theoretical results are demonstrated through two illustrative examples.
| Item Type: | Article |
|---|---|
| Subjects: | Q Science > QA Mathematics and Computer Science > QA75 Electronic computers. Computer science / számítástechnika, számítógéptudomány |
| Divisions: | Systems and Control Lab |
| SWORD Depositor: | MTMT Injector |
| Depositing User: | MTMT Injector |
| Date Deposited: | 17 Dec 2025 07:30 |
| Last Modified: | 17 Dec 2025 07:30 |
| URI: | https://eprints.sztaki.hu/id/eprint/11002 |
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