ATP production optimization in biochemical mass action models with protein turnover

Csercsik, Dávid and Szederkényi, Gábor (2013) ATP production optimization in biochemical mass action models with protein turnover. In: 1st IFAC Workshop on Thermodynamic Foundations of Mathematical Systems Theory, 2013-07-13 - 2013-07-16, Lyon, Franciaország.

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We introduce a simple approach to account for the ATP consumption and production in the case of mass action models of metabolic pathways including protein turnover. Under some simplifying assumptions, the method makes it possible to characterize the optimal rate of enzyme synthesis if the substrate concentrations and other rate constants are known. Furthermore we demonstrate that the proposed approach is capable of the comparison of the efficiency of different feedback laws in dynamic environment, considering time-varying substrate concentration. Copyright © 2013 IFAC.

Item Type: Conference or Workshop Item (-)
Uncontrolled Keywords: PROTEINS, System theory, RATE CONSTANTS, Substrate concentrations, Simplifying assumptions, Protein turnovers, Metabolic pathways, Mass action models, enzyme synthesis, Dynamic environments, Atp productions
Subjects: Q Science > QA Mathematics and Computer Science > QA75 Electronic computers. Computer science / számítástechnika, számítógéptudomány
Divisions: Systems and Control Lab
Depositing User: EPrints Admin
Date Deposited: 05 Feb 2014 12:32
Last Modified: 05 Feb 2014 15:46

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